Afuco™ Anti-Human IL31 ADCC Recombinant Antibody (BMS-981164), ADCC Enhanced
CAT#: AFC-409CL
Anti-IL31 ADCC Enhanced Antibody (BMS-981164) is an ADCC enhanced antibody produced by our Afuco™ platform. This is an anti-IL31 monoclonal antibody used as a potential treatment for atopic dermatitis, as well as for other diseases.
Tested Data
Gene Expression
WB
Figure 1 Human IL31 Recombinant Antibody (AFC-409CL) in WB
Western blot analysis of AFC-409CL was performed with IL31 Protein, Human, Recombinant (His Tag).
AFC-409CL incubation concentration: 2 ng/μL.
The secondary antibody: HRP-anti-human IgG
Lane 1: Reducing Antigen (0.1 μg)
Lane 2: Reducing Antigen (0.3 μg)
Lane 3: Reducing Antigen (0.6 μg)
ELISA
Figure 2 Human IL31 Recombinant Antibody (AFC-409CL) in ELISA
ELISA analysis of AFC-409CL was performed by coating with IL31 Protein, Human, Recombinant (His Tag).
The secondary antibody: HRP-anti-human IgG
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Normal Tissue
Figure 1 Cerebral cortex
Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_B_7_5.jpg
Normal Tissue
Figure 2 Kidney
Cells in glomeruli
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_A_7_5.jpg
Normal Tissue
Figure 3 Lymph node
Germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_A_8_8.jpg
Normal Tissue
Figure 4 Spleen
Cells in red pulp
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_B_9_4.jpg
RNA Expression
Figure 5 RNA cell line category: Not detected
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204671-IL31
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Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Atopic Dermatitis
Product Property
- Purity
- >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
- Storage
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Target
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# AFC-409CL, RRID: AB_3111278)
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| MOR-4266 | Rabbit Anti-Il31 Recombinant Antibody (clone SI348DS) | ELISA | Rabbit IgG |
| MOR-4617 | Rabbit Anti-IL31 Recombinant Antibody (clone TH130DS) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-419CQ | Anti-Canine IL31 Recombinant Antibody (TAB-419CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, κ |
| CAT | Product Name | Application | Type |
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| HPAB-0131-LSX | Mouse Anti-IL31 Recombinant Antibody (HPAB-0131-LSX) | ELISA, WB | Mouse IgG |
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| HPAB-0135-LSX | Canine Anti-IL31 Recombinant Antibody (HPAB-0135-LSX) | ELISA, WB | Canine IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0131-LSX-S(P) | Mouse Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0131-LSX-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0132-LSX-S(P) | Mouse Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0132-LSX-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0133-LSX-S(P) | Mouse Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0133-LSX-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0134-LSX-S(P) | Canine Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0134-LSX-S(P)) | ELISA, WB | Canine scFv |
| HPAB-0135-LSX-S(P) | Canine Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0135-LSX-S(P)) | ELISA, WB | Canine scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0131-LSX-F(E) | Mouse Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0131-LSX-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0132-LSX-F(E) | Mouse Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0132-LSX-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0133-LSX-F(E) | Mouse Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0133-LSX-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0134-LSX-F(E) | Canine Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0134-LSX-F(E)) | ELISA, WB | Canine Fab |
| HPAB-0135-LSX-F(E) | Canine Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0135-LSX-F(E)) | ELISA, WB | Canine Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-419CQ | Afuco™ Anti-IL31 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-419CQ) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY57 | Canine Anti-IL31 scFv-Fc Chimera (VS-0425-FY57) | ELISA | Canine IgG2, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3526 | Anti-IL31 Immunohistochemistry Kit | IHC |
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